pentobarbital will lower the extent or influence of diazepam intranasal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Solid or average CYP3A4 inducers may increase amount of diazepam elimination; thus, efficacy of diazepam might be reduced.pentobarbital will reduce the level or impact of elbasvir/grazoprevir by impact